I don't think there is one trick to it, no one special, magic method to make it big on Youtube n.n' Some people claim that their success was due to riding the hype on the right moments, others put all the praise in the SEO's, other go fully for audience interaction. I think you Youtube success will depend on all those little things combined.
If you upload regulary, but your content isn't of good quality, your upload schedule will not help you. And if you make a video about a viral topic, but your audio is aweful, nobody is going to watch it. I'd suggest you take a look around the forum and you will soon see that there are so many things that can help you grow!