A lot of people think gaming is super easy to do, but it's only because those who have been doing it for years make it look so easy. They've had all that time to develop a routine and familiarize themselves with their recording equipment. There's still the matter of syncing your audio with your video, making sure your microphone doesn't cut out, making sure your screen capture doesn't error, making sure your camera is recording - and then of course, there's the matter of needing the RAM on your computer to run the game and hoping you have something interesting to say while you're playing it!
Obviously, it's a lot easier to manage than some genres. For instance, you can record one whole gameplay in a single setting and easily break that down into several episodes to bulk out your channel. Animation can take weeks to months for just a few seconds, so major respect to anyone who can dedicate themselves to that.
I do educational comedy, so I have a few days each week to research, write up a script, check my sources, look for references, save websites and try and be funny. Recording in itself isn't too bad - camera on tripod and I'm good to go. No money for fancy lighting or additional equipment just yet. I just have to be quick as my camera only records in 20-minute segments and doesn't indicate when it's stopped. Also, natural light and the fact that I live on a main road can be a right pain in my butt, but I'm kind of used to all of that now.