I dont see why it would. I plan to put my face in the corner of my videos when i get a few more subs, and i dont think looks will do anything but help. Atleast for me doing gaming vids that is. I dont know if i will do a steady vlog set, but i would recommend that before you do a video just "Freshen up". Nothing crazy, i was in theater for a few years, and believe me, its ok for a dude to wear make up for the camera/audience. But that is, if you really think your looks are going to require a little big of cover up.