It mainly depends on your prospective. The viewer only needs to watch 5 to 10 second of the ad for you to be paid. So if you are more interested in the money I would enable these ads.
But if you care more about your watch time I don't recommend you to use these ads. As like shane said it will highly decrease your viewership since people just simple don't like ads at all.
I was personally confused when this ad format was added to my CMS around 3 weeks ago. I had to ask my PM what was this, what happen to the ad types. But overall I recommend not using them as I personally seen channels watch time and viewership drop on videos that have it enabled.