I've been catfished actually, but that's what cameras are for lol. If you can see them through the camera and watch their reactions, they can't hide much more about themselves than they can talking to you in a restaurant. I mean even in the flesh people can lie about themselves or mislead you, but if you can see them one thing they can't fake is what you feel from their eyes/body language/and most importantly that they're the person they claim to be in looks and gender etc.
From experience though, never EVER get into a relationship if you have not been on cam with the person with both visual AND audio. When I was catfished they muted the audio, used footage of another girl typing to someone on a camera and told me their mic was broken. Then they stopped communicating that way and told me their webcam broke. Not sure how people do it, but they can put visuals on skype that aren't coming from a real webcam, so if you cannot both see them AND hear that they are having a real conversation with their voice, don't trust it man..... just don't.