why not ?
These types of videos have a big potential on youtube, there are a lot of tinfoil-hats out there and most people are somewhat interested in funny/ridicoulus conspiracys.
If legit believe that Barack Obama is a lizard, you might not want to upload a video about that if you already have a settled audience, they might feel repulsive about that.
But otherwise, go for it.
Pretty easy and solid topic for a Vlog channel