See I don't think it's really the "YouTuber" part that would be useful on a resume but instead the portfolio of videos that you've created and edited and the artwork and thumbnails that you created for them. Also you could show that you have proven stats that show you know how to drive traffic with SEO or that you are good at understanding how to reach a target audience.
Of course they would not take "YouTuber" seriously by itself but they might take the numbers and content behind a successful channel seriously in terms of how you having those skills could help their business. You have to think in terms of what skills you can offer them that you gained from your YouTube experience such as, being self-driven, setting your own deadlines, showing leadership skills, knowledge of current SEO practices, your ability to drive traffic from scratch and gain exposure for their company to increase sales, understanding of what potential customers want to see, ability to successfully promote a brand or product, your technical editing/voice/filming skills, photoshop skills, social skills interacting and building your community to cultivate loyal customers. I would think you would have an advantage having analytics you could show that proved you executed a strategy to drive traffic and build a brand vs someone just has a degree but no experience in that. I'd argue many YouTubers are more skilled at building brands than many people who actually get paid to "manage" social media. But hey I'm not an employer atm so hard to really know, depends on the job you're applying it to.